Is topiramate taken on its own expected have any noteworthy diet/appetite/weight-loss effects? I know someone who’s on it to try and control their migraines.
Yup! It’s branded as “Topamax”, but I’ve heard that some users refer to it as “Stupamax” because of the brain fog effect. It doesn’t sound awesome.
Also, it sounded like it increases probability of getting a kidney stone by a lot, though I’d need to track down the reference. All told, feels like one of the worse options out there.
As far as I understand it, “combination” drugs don’t really do anything together that each component doesn’t do alone. For example, bupropion causes weight loss if you take it alone; it just causes more when you pair it with naltrexone, which also causes weight loss.
I could have imagined a case where the weight-loss effects were coming solely from the phentermine, with topiramate added to the combination for other reasons. But it having its own independent/added effect makes sense. For the person I know taking it, her appetite does seem quite reduced since switching from amitriptyline (I think that one increases appetite, so there will have been a double-effect from switching off that and onto something that suppresses it)
The brain fog is unfortunate, but also still less bad overall than the migraines were.
Is topiramate taken on its own expected have any noteworthy diet/appetite/weight-loss effects? I know someone who’s on it to try and control their migraines.
Yup! It’s branded as “Topamax”, but I’ve heard that some users refer to it as “Stupamax” because of the brain fog effect. It doesn’t sound awesome.
Also, it sounded like it increases probability of getting a kidney stone by a lot, though I’d need to track down the reference. All told, feels like one of the worse options out there.
As far as I understand it, “combination” drugs don’t really do anything together that each component doesn’t do alone. For example, bupropion causes weight loss if you take it alone; it just causes more when you pair it with naltrexone, which also causes weight loss.
God to know, thanks.
I could have imagined a case where the weight-loss effects were coming solely from the phentermine, with topiramate added to the combination for other reasons. But it having its own independent/added effect makes sense. For the person I know taking it, her appetite does seem quite reduced since switching from amitriptyline (I think that one increases appetite, so there will have been a double-effect from switching off that and onto something that suppresses it)
The brain fog is unfortunate, but also still less bad overall than the migraines were.