So you can generate a killed virus vaccine with heat or chemicals as well.
This method just doesn’t generate a very strong immune response compared to live attenuated vaccines. You need an adjuvant. I am guessing having some cells infected by a live virus contributes to a full immune response (induce CD8 T cells etc).
So you can generate a killed virus vaccine with heat or chemicals as well.
This method just doesn’t generate a very strong immune response compared to live attenuated vaccines. You need an adjuvant. I am guessing having some cells infected by a live virus contributes to a full immune response (induce CD8 T cells etc).