We pretty much know how to deal with even the most severe pain—very large doses of opiates to get rid of it, and large doses of stimulants like amphetamines to counter the side effects.
I’d be incredibly surprised if this actually worked clinically.
That doesn’t answer my question. I’m not interested in the ethical, legal, and societal barriers to adequate pain management, which is what your link covers as far as I can tell.
I want to know how one intends to circumvent opiate tolerance, and whether or not large doses of stimulants really do counteract the side effects of large doses of opiates in a large enough class of people to be effective, without the side effects of these stimulants becoming undesirable.
Assembling a drug cocktail in order to achieve some central result while minimizing side effects, with ongoing adjustment as the severity of the underlying condition and the patient’s sensitivity to the drugs in question both change, is one of those complicated problems which modern medicine is nonetheless capable of solving, given adequate resources.
I’d be incredibly surprised if this actually worked clinically.
Start here, and follow the links.
That doesn’t answer my question. I’m not interested in the ethical, legal, and societal barriers to adequate pain management, which is what your link covers as far as I can tell.
I want to know how one intends to circumvent opiate tolerance, and whether or not large doses of stimulants really do counteract the side effects of large doses of opiates in a large enough class of people to be effective, without the side effects of these stimulants becoming undesirable.
Assembling a drug cocktail in order to achieve some central result while minimizing side effects, with ongoing adjustment as the severity of the underlying condition and the patient’s sensitivity to the drugs in question both change, is one of those complicated problems which modern medicine is nonetheless capable of solving, given adequate resources.