Fair. I doubt there would be THAT much value drift due to personality changes just because there’s not that much plieotropy in the genome. But it also wouldn’t be literally zero.
And you could always opt for a lesser effect size by just targeting fewer genes and testing yourself after some time period to assess values drift before deciding if you want to go forward with a larger intervention.
That is one of the nice things about this proposal; if it works well you could will be able to customize the effect size.
I’d be worried about changes to my personality or values from editing so many brain relevant genes.
Fair. I doubt there would be THAT much value drift due to personality changes just because there’s not that much plieotropy in the genome. But it also wouldn’t be literally zero.
And you could always opt for a lesser effect size by just targeting fewer genes and testing yourself after some time period to assess values drift before deciding if you want to go forward with a larger intervention.
That is one of the nice things about this proposal; if it works well you could will be able to customize the effect size.