If the temperature is high enough that there’s molecular movement at all, you could observe a collection of proteins every Planck-instant and see a (slightly) different arrangement each time. You might be stuck with similar ones, especially stable configurations, for a long time… but that’s exactly the sort of bias that makes life possible.
You shouldn’t use Planck times unless the protean can rearrange themselves that quickly.
If the temperature is high enough that there’s molecular movement at all, you could observe a collection of proteins every Planck-instant and see a (slightly) different arrangement each time. You might be stuck with similar ones, especially stable configurations, for a long time… but that’s exactly the sort of bias that makes life possible.