I recommend anyone considering SSRIs to consider Silexan. See this write-up from Scott Alexander which covers the research. Someone I know has replaced their SSRI with Silexan. Several people I know have had good experiences. The main, and not always common, side effect is lavender flavored burps. Not everyone gets it. I don’t, and it wasn’t bad when I did. No-one I know has had a bad experience. Overall, the downside risk appears to be relatively low.
As I understand it, there are several studies showing that it works for depression. Of course, it may be the case that this is only for people for whom anxiety caused the depression.
Yes, the first two of those do mention co-occurring anxiety in the title.
The third study suggests a possibility that it might just work as an effective anti-depressant as well. (I hope there will be further studies like that; yes, this might be a sufficient reason to try it for depression, even if one does not have anxiety. It might work, but it’s clearly not a common knowledge yet.)
I recommend anyone considering SSRIs to consider Silexan. See this write-up from Scott Alexander which covers the research. Someone I know has replaced their SSRI with Silexan. Several people I know have had good experiences. The main, and not always common, side effect is lavender flavored burps. Not everyone gets it. I don’t, and it wasn’t bad when I did. No-one I know has had a bad experience. Overall, the downside risk appears to be relatively low.
For anxiety treatment only, if I understand it correctly.
There is no claim that it works as an antidepressant, as far as I know.
As I understand it, there are several studies showing that it works for depression. Of course, it may be the case that this is only for people for whom anxiety caused the depression.
E.g.,
https://pubmed.ncbi.nlm.nih.gov/26718792/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9958187/#:~:text=After%2010%2Dweek%20treatment%2C%20patients,studies%3B%20p%20%3C%200.01).
https://link.springer.com/article/10.1007/s00406-024-01783-2
Thanks for the references.
Yes, the first two of those do mention co-occurring anxiety in the title.
The third study suggests a possibility that it might just work as an effective anti-depressant as well. (I hope there will be further studies like that; yes, this might be a sufficient reason to try it for depression, even if one does not have anxiety. It might work, but it’s clearly not a common knowledge yet.)