I was under the impression that loss of sense of smell was primarily happening to people who take zinc intranasally. (I don’t have numbers handy.)
My impression was that the effect of the zinc was supposed to be on the virus (or the virus’s interaction with your cells), not on the body. Which (if true) would seem to imply that prophylactic use shouldn’t cause adaptation.
This paper appears to be a discussion of a Cochrane review from 2011, and supports prophylactic use (and also generally supports use, and provides more info):
(Irritatingly, there have been a number of subsequent versions of the Cochrane review, but several of them have been withdrawn, for reasons that are hard for me to interpret, although one at least involved an accusation of plagiarism from another meta-review on the same topic. It feels to me like there may be some kind of political fight over ownership of this Cochrane review.)
I was under the impression that loss of sense of smell was primarily happening to people who take zinc intranasally. (I don’t have numbers handy.)
My impression was that the effect of the zinc was supposed to be on the virus (or the virus’s interaction with your cells), not on the body. Which (if true) would seem to imply that prophylactic use shouldn’t cause adaptation.
This paper appears to be a discussion of a Cochrane review from 2011, and supports prophylactic use (and also generally supports use, and provides more info):
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3273967/
The 2011 version of the Cochrane review in question: https://www.ncbi.nlm.nih.gov/pubmed/21328251 / http://sci-hub.tw/10.1002/14651858.CD001364.pub3
(Irritatingly, there have been a number of subsequent versions of the Cochrane review, but several of them have been withdrawn, for reasons that are hard for me to interpret, although one at least involved an accusation of plagiarism from another meta-review on the same topic. It feels to me like there may be some kind of political fight over ownership of this Cochrane review.)
ALSO, while looking through Cochrane reviews, I found this one in favor of Vitamin C for the common cold: https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD000980.pub4/full