I think in order to quantify risk-vs-number-of-vaccinations, we need to understand the type of risk itself and how the vaccine might have unintended effects. If we assume all of the unintended effects are longer-than-expected presence of the mRNA (or otherwise vector) and its derivatives, then the risk of noticeable adverse consequences doesn’t really sum up because any accumulation effects will be negligible. I.e. the amount of substance is low − 1 ng/kg body mass is same as 2 ng/kg body mass. Relatively it’s a lot but it’s not a lot if consider the body a “resilient/tolerant” system.
I think in order to quantify risk-vs-number-of-vaccinations, we need to understand the type of risk itself and how the vaccine might have unintended effects. If we assume all of the unintended effects are longer-than-expected presence of the mRNA (or otherwise vector) and its derivatives, then the risk of noticeable adverse consequences doesn’t really sum up because any accumulation effects will be negligible. I.e. the amount of substance is low − 1 ng/kg body mass is same as 2 ng/kg body mass. Relatively it’s a lot but it’s not a lot if consider the body a “resilient/tolerant” system.