The science is solid for naltrexon low dose therapy which is used to up-regulate opiate receptors. The idea is to use small doses of antagonist to make the exiting receptors more sensible after some period of time. The same principle could be applied to other depressants, including melatonin, which start to simulate because of withdrawal effects.
I am unfamiliar with the science here—what is the difference between a “reversed-effect stimulant” and a depressant?
The science is solid for naltrexon low dose therapy which is used to up-regulate opiate receptors. The idea is to use small doses of antagonist to make the exiting receptors more sensible after some period of time. The same principle could be applied to other depressants, including melatonin, which start to simulate because of withdrawal effects.