True, and this does indicate that children produced from genes found in 2 parents will not be outside the range which a hypothetical natural child of theirs could occupy. I am also hopeful that this is what matters, here.
However, there are absolutely, definitely viable combinations of genes found in a random pair of parents which, if combined in a single individual, result in high-IQ offspring predisposed to any number of physical or mental problems, some of which may not manifest until long after the child is born. In practice, any intervention of the type proposed here seems likely to create many children with specific combinations of genes which we know are individually helpful for specific metrics, but which may not often (or ever) have all co-occurred. This is true even in the cautious, conservative early generations where we stay within the scope of natural human variations. Thereafter, how do we ensure we’re not trialing someone on an entire generation at once? I don’t want us to end up in a situation where a single mistake ends up causing population-wide problems because we applied it to hundreds of millions of people before the problem manifested.
True, and this does indicate that children produced from genes found in 2 parents will not be outside the range which a hypothetical natural child of theirs could occupy. I am also hopeful that this is what matters, here.
However, there are absolutely, definitely viable combinations of genes found in a random pair of parents which, if combined in a single individual, result in high-IQ offspring predisposed to any number of physical or mental problems, some of which may not manifest until long after the child is born. In practice, any intervention of the type proposed here seems likely to create many children with specific combinations of genes which we know are individually helpful for specific metrics, but which may not often (or ever) have all co-occurred. This is true even in the cautious, conservative early generations where we stay within the scope of natural human variations. Thereafter, how do we ensure we’re not trialing someone on an entire generation at once? I don’t want us to end up in a situation where a single mistake ends up causing population-wide problems because we applied it to hundreds of millions of people before the problem manifested.