Well, if viewing it on that level, AlphaFold 2 didn’t crack the full problem because it doesn’t let you put in a chemical function and get out a protein which performs that function while subject to other constraints of a surrounding wet system, which is the protein folding problem you have to solve to get wet nanotech out the other end, which is why we don’t already have general wet nanotech today.
Well, if viewing it on that level, AlphaFold 2 didn’t crack the full problem because it doesn’t let you put in a chemical function and get out a protein which performs that function while subject to other constraints of a surrounding wet system, which is the protein folding problem you have to solve to get wet nanotech out the other end, which is why we don’t already have general wet nanotech today.