I think the easiest way to do these kinds of self-experiments is just to wait a long time, say 6 months, or maybe a year, between doing each branch of the experiment. If you do a lots of these self-experiments, then you really won’t remember at all the minutia of what you did the first time. I think taking roofies regularly in order to learn these little things about yourself has massively negative expected payoff, though I guess taking them once to see if the concept itself works wouldn’t be too destructive.
I think the easiest way to do these kinds of self-experiments is just to wait a long time, say 6 months, or maybe a year, between doing each branch of the experiment. If you do a lots of these self-experiments, then you really won’t remember at all the minutia of what you did the first time. I think taking roofies regularly in order to learn these little things about yourself has massively negative expected payoff, though I guess taking them once to see if the concept itself works wouldn’t be too destructive.