Not getting the shoot because you don’t trust the calculation in the OP is completely different then not getting the shot because not trusting cold chain messups.
1⁄500 is lower then the uncertainty in the effect size of the vaccine.
I was saying you should get the second shot just in case your immune system didn’t develop a robust response the first time (biology is stochastic and not a digital system) or because the cold chain or manufacturing chain rushing the shots had an error.
Even if on paper the gain is either 0 or marginal.
For administrators planning vaccinations of a populance, of course the evidence strongly says first doses first, you shouldn’t even start with second does until all willing individuals have their first.
Not getting the shoot because you don’t trust the calculation in the OP is completely different then not getting the shot because not trusting cold chain messups.
1⁄500 is lower then the uncertainty in the effect size of the vaccine.
I was saying you should get the second shot just in case your immune system didn’t develop a robust response the first time (biology is stochastic and not a digital system) or because the cold chain or manufacturing chain rushing the shots had an error.
Even if on paper the gain is either 0 or marginal.
For administrators planning vaccinations of a populance, of course the evidence strongly says first doses first, you shouldn’t even start with second does until all willing individuals have their first.