Bell mentions this paper in Nature Medicine that finds only 2.3% of people having symptoms after 12 weeks. (The UK ONS study that is Bell’s main sources estimates 13%). It seems better to take a mean of these estimates than to just drop one of them, as the studies are fairly similar in approach. (Both rely on self-report. The sample size for the Nature paper is >4000).
Note that the 13% figure in the ONS study drops to 1% if you restrict to subjects who had symptoms every week. (The study allows for people to go a week without any symptoms while still counting as a Long Covid case). I realize people report Long Covid as varying over time, but it’s clearly worse to have a condition that causes some fatigue or tiredness at least once a week rather at least once every two weeks.
(Do you mean the Lancet / British intelligence test paper when you say ONS? I embarrassingly don’t see a paper I cited with those letters in it.)
The current way I imagine citing this is to use as a corroboration of my rough estimate of <2% 30yos having Long COVID. I don’t see an easy way to integrate it with IQ loss estimates—since I wouldn’t expect tiny levels of IQ loss to show up on a survey about actual Long COVID symptoms, it seems relatively consistent for 2% symptoms after 12 weeks to still correspond to an average IQ loss of .15 points after 12 weeks (~10% lose 1 IQ point, 1% lose several IQ points). I do think it points downwards somewhat, though, maybe a factor of 2?
I added a link above. The ONS is the UK’s national statistics agency. This is not a peer-reviewed paper but a report they published. (I find these reports to be mixed in quality).
In the Nature paper, they get 2.3% with symptoms overall. But they estimate that 30 yos are less likely than older cohorts to have symptoms at 56 days and so you could adjust down a bit. (Women are also at higher risk according to this study).
Bell mentions this paper in Nature Medicine that finds only 2.3% of people having symptoms after 12 weeks. (The UK ONS study that is Bell’s main sources estimates 13%). It seems better to take a mean of these estimates than to just drop one of them, as the studies are fairly similar in approach. (Both rely on self-report. The sample size for the Nature paper is >4000).
Note that the 13% figure in the ONS study drops to 1% if you restrict to subjects who had symptoms every week. (The study allows for people to go a week without any symptoms while still counting as a Long Covid case). I realize people report Long Covid as varying over time, but it’s clearly worse to have a condition that causes some fatigue or tiredness at least once a week rather at least once every two weeks.
Great paper, thank you!
(Do you mean the Lancet / British intelligence test paper when you say ONS? I embarrassingly don’t see a paper I cited with those letters in it.)
The current way I imagine citing this is to use as a corroboration of my rough estimate of <2% 30yos having Long COVID. I don’t see an easy way to integrate it with IQ loss estimates—since I wouldn’t expect tiny levels of IQ loss to show up on a survey about actual Long COVID symptoms, it seems relatively consistent for 2% symptoms after 12 weeks to still correspond to an average IQ loss of .15 points after 12 weeks (~10% lose 1 IQ point, 1% lose several IQ points). I do think it points downwards somewhat, though, maybe a factor of 2?
I added a link above. The ONS is the UK’s national statistics agency. This is not a peer-reviewed paper but a report they published. (I find these reports to be mixed in quality).
In the Nature paper, they get 2.3% with symptoms overall. But they estimate that 30 yos are less likely than older cohorts to have symptoms at 56 days and so you could adjust down a bit. (Women are also at higher risk according to this study).
Oops, thought that was a top-level reply to me when I clicked on it, rather than a reply to Adam. Sorry. Makes more sense in context.