In the hospital, we usually give 1g IV for any real pain. I don’t think the notion that giving more of a painkiller would produce a stronger effect is particularly controversial!
(Anecdotally, the IV route is somewhat more effective, even though the nominal bioavailability is the same as the oral route. It might be down to faster onset and the placebo aspect of assuming anything given by a drip is “stronger”)
In the hospital, we usually give 1g IV for any real pain. I don’t think the notion that giving more of a painkiller would produce a stronger effect is particularly controversial!
(Anecdotally, the IV route is somewhat more effective, even though the nominal bioavailability is the same as the oral route. It might be down to faster onset and the placebo aspect of assuming anything given by a drip is “stronger”)