cold-chain requirements had more margin for error than any of us had thought
the process that produced excess margin for error in this case likely produced excess margin for error in other relevant areas
(tentative) Should this make less plausible a line of reasoning that goes through “Except sometimes vaccines are left at high temperature for too long, the delicate proteins are damaged, and people receiving them are effectively not vaccinated...”? I’m not sure yet, and I don’t know how central this particular line is to the overall argument.
That makes sense, and now you mention it, I heard the same about injectable monoclonal antibodies. At first they thought a few hours at room temperature would destroy them, turned out that’s probably false.
Related: https://marginalrevolution.com/marginalrevolution/2021/05/cold-storage-no-longer-a-constraint.html suggests that:
cold-chain requirements had more margin for error than any of us had thought
the process that produced excess margin for error in this case likely produced excess margin for error in other relevant areas
(tentative) Should this make less plausible a line of reasoning that goes through “Except sometimes vaccines are left at high temperature for too long, the delicate proteins are damaged, and people receiving them are effectively not vaccinated...”? I’m not sure yet, and I don’t know how central this particular line is to the overall argument.
That makes sense, and now you mention it, I heard the same about injectable monoclonal antibodies. At first they thought a few hours at room temperature would destroy them, turned out that’s probably false.