Seems to be of great practical significance to me. If there’s a decent chance that I could return completely to unlimited degrees of interpersonal close contact and have only a 1⁄20 − 1⁄100 chance of getting symptomatic Covid with unlimited amounts of exposure, even if I would get covid many times over while unvaccinated, I’d be quite tempted to do it. If returning to that level of exposure would mean that I’d almost inevitably get Covid eventually, I’d be much more likely to play it safe for at least a few months more and see where things go with infection rates and new variants.
Seems to be of great practical significance to me. If there’s a decent chance that I could return completely to unlimited degrees of interpersonal close contact and have only a 1⁄20 − 1⁄100 chance of getting symptomatic Covid with unlimited amounts of exposure, even if I would get covid many times over while unvaccinated, I’d be quite tempted to do it. If returning to that level of exposure would mean that I’d almost inevitably get Covid eventually, I’d be much more likely to play it safe for at least a few months more and see where things go with infection rates and new variants.