Yeah, this has been confusing me as well. There’s an antigen test that Roche claims has 96.52% sensitivity (so <4% false negatives), which seems both surprisingly high (since even PCR tests seem to have far lower sensitivity, as per the study you linked) and suspiciously precise.
Yeah, this has been confusing me as well. There’s an antigen test that Roche claims has 96.52% sensitivity (so <4% false negatives), which seems both surprisingly high (since even PCR tests seem to have far lower sensitivity, as per the study you linked) and suspiciously precise.
With antigen tests, I believe the figures are “P(positive test | positive gold standard test)”
Look at the documentation for another antigen test—section 14 gives sensitivity compared to PCR. The figure they promote (and is e.g. used for the German government approval) is 97.56% sensitivity. This is both based on PCR, and based on filtering down to specimens with a high viral load (Ct 20-30).
BTW, that German site is a good collection of documentation links for all the antigen tests currently approved.
Ah, gotcha, that makes more sense. And thanks for the awesome antigen test table you linked there!