From my understanding of how the learned immune response works an infection has to grow to a certain size before it really starts to kick in. That would tend to suggest that, if a dose is enough to cause an infection in the first place, danger will remain roughly constant up to some inflection point before starting to become less dangerous.
Of course as doses go down the chance that the innate immune system cleans it up or none of the viruses manage to find an ACE2 receptor goes up. But in those cases you won’t be training the immune system.
From my understanding of how the learned immune response works an infection has to grow to a certain size before it really starts to kick in. That would tend to suggest that, if a dose is enough to cause an infection in the first place, danger will remain roughly constant up to some inflection point before starting to become less dangerous.
Of course as doses go down the chance that the innate immune system cleans it up or none of the viruses manage to find an ACE2 receptor goes up. But in those cases you won’t be training the immune system.