There’s a another option for getting IVF to give you a better range of choices with no tricky cell line manipulation… Surgically remove the mother-to-be’s ovaries. Dissect them and extract all the egg cells. Fertilize all the egg cells with the father-to-be’s sperm. Then you get to do polygenic selection on the ‘full set’ instead of just a few candidates.
Apart from coming across as quite repulsive to most people, I wonder at the cost and success rate of maturing immature oocytes.
This is already an issue for child cancer patients who want to preserve future fertility but haven’t hit puberty yet. As of 2021, there were only ~150 births worldwide using this technique.
The costs are also going to be a major issue here. Gain scales with sqrt(ln(number of embryos)). But cost per embryo produced and tested scales almost linearly. So the cost per IQ point is going to scale at like ex2, which is hilariously, absurdly bad.
I’d also want to see data on the number of immature oocytes we could actually extract with this technique, the rate at which those immature oocytes could be converted into mature oocytes, and the cost per oocyte.
There’s a another option for getting IVF to give you a better range of choices with no tricky cell line manipulation… Surgically remove the mother-to-be’s ovaries. Dissect them and extract all the egg cells. Fertilize all the egg cells with the father-to-be’s sperm. Then you get to do polygenic selection on the ‘full set’ instead of just a few candidates.
Apart from coming across as quite repulsive to most people, I wonder at the cost and success rate of maturing immature oocytes.
This is already an issue for child cancer patients who want to preserve future fertility but haven’t hit puberty yet. As of 2021, there were only ~150 births worldwide using this technique.
The costs are also going to be a major issue here. Gain scales with sqrt(ln(number of embryos)). But cost per embryo produced and tested scales almost linearly. So the cost per IQ point is going to scale at like ex2, which is hilariously, absurdly bad.
I’d also want to see data on the number of immature oocytes we could actually extract with this technique, the rate at which those immature oocytes could be converted into mature oocytes, and the cost per oocyte.