my somewhat admittedly sketchy reasoning:
I go to the University of Washington where there is considerable interest in the case. Of the people who have only been marginally involved in the case, most believe that Amanda Knox is innocent. Of the people who are interested in the case, many believe she is guilty. There’s an obvious hometown effect here which biases towards innocence so I’m assuming those who look into the case are taking that into account when and still reach a guilty verdict.
Therefore, I assign a 70% probability to Amanda Knox being guilty (+ or − 30%).
Wasn’t there a post here a while back that talked about how anyone positing a confidence of 0.999 on something non-trivial was most likely to be suffering from their own cognitive biases?