Couple of things… A leap ahead in computing would not necessarily mean that Moore’s Law was not descriptive of the event. It could still follow the same exponential trend, yet look like a giant leap forward.
It is likely that Moore’s Law will continue due to economic pressure to find newer and faster ways to compute. This may not have to do with shrinking transistor sized, but may well involve other forms of computation or architecture for chips.
According to the guy from Intel (Justin Ratner) at the 2008 Singularity Summit. Moore’s Law ended in 2005⁄06. The discrete transistor is a thing of the past according to his talk.