“What takes real courage is braving the outright incomprehension of the people around you,”
I suspect that autistics are far more willing than neurotypicals to be true iconoclast because many neurotypicals find autistics incomprehensible regardless of what the autistics believe. So the price of being an intellectual iconoclast is lower for autistics than for most other people.
If we assume that Omega almost never makes a mistake and we allow the chooser to use true randomization (perhaps by using quantum physics) in making his choice, then Omega must make his decision in part through seeing into the future. In this case the chooser should obviously pick just B.