Large breed dogs often die of heart disease which is often due to dilated cardiomyopathy (heart becomes enlarged and can’t pump blood effectively). This enlargement can come from hypertrophic cardiomyopathy (overgrowth of the heart muscle).
Dilated cardiomyopathy and hypertrophic cardiomyopathy are two different conditions that I’ve not seen co-occur. They are basically sign-flipped versions of each other.
Dilated cardiomyopathy is when heart tissue becomes weaker and thinner. It stretches out like an overfilled balloon, and can’t beat with the same strength. Symptoms include tiredness, shortness of breath, in severe cases progressing into inability to circulate blood (heart failure).
Hypertrophic cardiomyopathy is when the heart tissue becomes stronger and thicker. The inner heart space becomes too narrow and can cause a heart valve to get stuck in the “closed” position, stopping the outflow of blood. This type of cardiomyopathy often stays asymptomatic and undiagnosed by routine checkups, until one day a young athletic person presents with a symptom of “sudden cardiac death”.
The only feature they both share in common that comes to mind is that the heart becomes larger on X-ray (Cardiomegaly).
Dilated cardiomyopathy and hypertrophic cardiomyopathy are two different conditions that I’ve not seen co-occur. They are basically sign-flipped versions of each other.
Dilated cardiomyopathy is when heart tissue becomes weaker and thinner. It stretches out like an overfilled balloon, and can’t beat with the same strength. Symptoms include tiredness, shortness of breath, in severe cases progressing into inability to circulate blood (heart failure).
Hypertrophic cardiomyopathy is when the heart tissue becomes stronger and thicker. The inner heart space becomes too narrow and can cause a heart valve to get stuck in the “closed” position, stopping the outflow of blood. This type of cardiomyopathy often stays asymptomatic and undiagnosed by routine checkups, until one day a young athletic person presents with a symptom of “sudden cardiac death”.
The only feature they both share in common that comes to mind is that the heart becomes larger on X-ray (Cardiomegaly).
Thanks for the clarification! Do you know if either condition is associated with abnormal levels of IGF-1 or other growth hormones?