This seems right, but also interested in whether boosters might be net-harmful v.s. nothing.
Does original antigenic sin also mean that e.g. your body would have a harder time fighting off omicron if infected, because rather than developing new antibodies it would just keep trying to deploy the old ones?
If we have data that boosters reduce severity for omicron, that would seem to answer this. But do we?
Again, I did not look into much detail—so feel free to look at zvi’s newer post with some updated data—but overall weight seems in favor of booster more than when I made this comment.
This seems right, but also interested in whether boosters might be net-harmful v.s. nothing.
Does original antigenic sin also mean that e.g. your body would have a harder time fighting off omicron if infected, because rather than developing new antibodies it would just keep trying to deploy the old ones?
If we have data that boosters reduce severity for omicron, that would seem to answer this. But do we?
I have not looked into much, but saw what looks like more evidence that boosters do help: https://mobile.twitter.com/DataDrivenMD/status/1469448926562455555
Again, I did not look into much detail—so feel free to look at zvi’s newer post with some updated data—but overall weight seems in favor of booster more than when I made this comment.
Very interested in this question as well.