You’re right—it’s what we would expect. And yet the actual blood aluminum levels we measure aren’t that high! So where is all the aluminum? Well, biopsies show that kidneys have something like 10x the AL levels of other soft tissues in rabbits, so I suspect that’s where a lot of the aluminum goes during the first hour. This is then excreted in urine, explaining why urine AL levels are sometimes higher than blood AL levels. After that, tissues slowly release their aluminum into the bloodstream, where they get absorbed by the kidneys before blood AL levels can rise too much. Sounds nice in theory, but probably more complicated/downright wrong in practice.
You’re right—it’s what we would expect. And yet the actual blood aluminum levels we measure aren’t that high! So where is all the aluminum? Well, biopsies show that kidneys have something like 10x the AL levels of other soft tissues in rabbits, so I suspect that’s where a lot of the aluminum goes during the first hour. This is then excreted in urine, explaining why urine AL levels are sometimes higher than blood AL levels. After that, tissues slowly release their aluminum into the bloodstream, where they get absorbed by the kidneys before blood AL levels can rise too much. Sounds nice in theory, but probably more complicated/downright wrong in practice.
Will do more research tomorrow.