The particular vaccine (MVA-BN / Imvanex / Jynneos) that has been shown to be effective for monkeypox is administered via injection[1] not scarification. Stored frozen, it has an approved shelf life of 36 months[1]. In 2014 the US had 24 million doses stockpiled[2]; As far as I can tell, the stockpile is around 1 million doses now[3].
There are also 100 million doses[3] of the scarifying (ACAM2000) vaccine that hasn’t been studied for monkeypox; Stored dry, that has an approved shelf life of 18 months[4]. It is not currently clear to me how much of the stockpile is beyond its expiration date.
If the FDA requires EUAs for the expired vaccines[5], how long that regulatory process will take and how useful vaccination will be by that point are open questions.
The particular vaccine (MVA-BN / Imvanex / Jynneos) that has been shown to be effective for monkeypox is administered via injection[1] not scarification. Stored frozen, it has an approved shelf life of 36 months[1]. In 2014 the US had 24 million doses stockpiled[2]; As far as I can tell, the stockpile is around 1 million doses now[3].
There are also 100 million doses[3] of the scarifying (ACAM2000) vaccine that hasn’t been studied for monkeypox; Stored dry, that has an approved shelf life of 18 months[4]. It is not currently clear to me how much of the stockpile is beyond its expiration date.
If the FDA requires EUAs for the expired vaccines[5], how long that regulatory process will take and how useful vaccination will be by that point are open questions.
[1] https://www.fda.gov/media/131802/download
[2] https://www.niaid.nih.gov/diseases-conditions/smallpox-vaccine
[3] https://www.nbcnews.com/science/science-news/smallpox-vaccines-protect-against-monkeypox-stockpiled-rcna29919
[4] https://www.health.mil/Reference-Center/Policies/2008/01/31/Transition-to-ACAM2000-Smallpox-Vaccine
[5] https://www.fda.gov/emergency-preparedness-and-response/mcm-legal-regulatory-and-policy-framework/expiration-dating-extension