The Medina study received some methodological complains, see the JAMA letter.
Ivermectin proponents seem to consistently push for a regimen of:
high dosage (0.2mg/kg once-a-week for prevention)
early usage, ideally as prevention
usage with/after meals
If they’re right one can imagine studies that see no effects either because of low dosage, late administration or administering it on empty stomach (the anti-parasite regimen), which the Medina study does.
That’s super-helpful—thanks!
One thing the negative meta-study noted was the variation in doses between studies (12 − 210mg).
The Medina study received some methodological complains, see the JAMA letter.
Ivermectin proponents seem to consistently push for a regimen of:
high dosage (0.2mg/kg once-a-week for prevention)
early usage, ideally as prevention
usage with/after meals
If they’re right one can imagine studies that see no effects either because of low dosage, late administration or administering it on empty stomach (the anti-parasite regimen), which the Medina study does.
That’s super-helpful—thanks!
One thing the negative meta-study noted was the variation in doses between studies (12 − 210mg).