This test put that possibility to rest: after snorting just the peptides, I was very obviously congested for a couple days, in basically the same way as after the vaccine doses.
That seems pretty strong evidence to me.
I would do a placebo control too, just to make sure.
I would do a placebo control too, just to make sure.
My prior that snorting DI water would do nothing was pretty strong, but I had intended to test it anyway, so thanks for the reminder.
I snorted some DI water last night, in the same manner that I snorted vaccine/peptides. With the vaccine/peptides, I pretty consistently woke up congested the next morning, and blew my nose every few minutes throughout the day. None of that has happened with the DI water—it’s just been a normal day so far, in terms of congestion.
I’m not sure DI water would be a suitable “placebo” here. Perhaps a placebo effect is not even what is occurring. Previously you were inhaling something with small particles—a bit like what happens every spring with pollen. Perhaps a test with some other inert matter that might not even be able to invade your body much less produce some type of chemical reactions with the cells or cellular processes?
Yeah, that had occurred to me too. If people have other suggestions for what to snort, I’m open to ideas. Though my priors are still pretty strong here—I’ve accidentally snorted enough things to know that most things don’t induce significant congestion.
Ok this may be a naive question, but given that John brews the stuff and expects certain results anyway: Isn’t being congested something that might simply follow from actual placebo effects?
That is definitely something to worry about. I would be very surprised if the degree of congestion I experienced could be induced by a placebo effect, but this is exactly the sort of reason why I said the result lacks legibility—the rest of you haven’t been able to see exactly what the symptoms looked like.
Effective blinding is definitely more involved if one’s both experimenter and test subject. It’s not impossible but an assistant would help a lot. Controlling for placebo effect does seem one of the big issues at this scale.
I could prep both some peptides and a control and have my girlfriend randomly pick one, although the peptides do have a detectable scent to them, so I don’t think this would be enough to actually blind me.
You could add some other scented ingredient to both peptide and control solutions. Rosewater would be a pleasant option. I wouldn’t expect this to interfere with any immune responses too much, but you should do some research to check if you decide to try this.
That seems pretty strong evidence to me.
I would do a placebo control too, just to make sure.
My prior that snorting DI water would do nothing was pretty strong, but I had intended to test it anyway, so thanks for the reminder.
I snorted some DI water last night, in the same manner that I snorted vaccine/peptides. With the vaccine/peptides, I pretty consistently woke up congested the next morning, and blew my nose every few minutes throughout the day. None of that has happened with the DI water—it’s just been a normal day so far, in terms of congestion.
I’m not sure DI water would be a suitable “placebo” here. Perhaps a placebo effect is not even what is occurring. Previously you were inhaling something with small particles—a bit like what happens every spring with pollen. Perhaps a test with some other inert matter that might not even be able to invade your body much less produce some type of chemical reactions with the cells or cellular processes?
Yeah, that had occurred to me too. If people have other suggestions for what to snort, I’m open to ideas. Though my priors are still pretty strong here—I’ve accidentally snorted enough things to know that most things don’t induce significant congestion.
Ok this may be a naive question, but given that John brews the stuff and expects certain results anyway: Isn’t being congested something that might simply follow from actual placebo effects?
That is definitely something to worry about. I would be very surprised if the degree of congestion I experienced could be induced by a placebo effect, but this is exactly the sort of reason why I said the result lacks legibility—the rest of you haven’t been able to see exactly what the symptoms looked like.
Effective blinding is definitely more involved if one’s both experimenter and test subject. It’s not impossible but an assistant would help a lot. Controlling for placebo effect does seem one of the big issues at this scale.
I could prep both some peptides and a control and have my girlfriend randomly pick one, although the peptides do have a detectable scent to them, so I don’t think this would be enough to actually blind me.
You could add some other scented ingredient to both peptide and control solutions. Rosewater would be a pleasant option. I wouldn’t expect this to interfere with any immune responses too much, but you should do some research to check if you decide to try this.