Oops, missed this. I don’t check LW messages much.
20% was not an exact value. At the time I wasn’t aware of any estimates. Since then I’ve heard that the standard curve fit returns a ~50% growth per 6.5 days, some or all of which may be due to immune escape.)
I had a couple assumptions that made me think the SA strain was less contagious in expectation:
High contagiousness is more likely when high mutation numbers were seen, and correspondingly emergence would tend to be later. The SA variant gained local dominance earlier than the UK.
There was (and is) much less data on the SA variant. Due to the high variation in number of infectees per sick person, my prior is that on average, a variant that seems to be gaining ground is not as infectious as a curve fit implies, because luck could be a big factor and is more common than extreme fitness.
Oops, missed this. I don’t check LW messages much.
20% was not an exact value. At the time I wasn’t aware of any estimates. Since then I’ve heard that the standard curve fit returns a ~50% growth per 6.5 days, some or all of which may be due to immune escape.)
I had a couple assumptions that made me think the SA strain was less contagious in expectation:
High contagiousness is more likely when high mutation numbers were seen, and correspondingly emergence would tend to be later. The SA variant gained local dominance earlier than the UK.
There was (and is) much less data on the SA variant. Due to the high variation in number of infectees per sick person, my prior is that on average, a variant that seems to be gaining ground is not as infectious as a curve fit implies, because luck could be a big factor and is more common than extreme fitness.