[Question] What is an appropriate sample size when surveying billions of data points?

I am surveying Internet web accessibility. We’re hoping to draw big conclusions on how accessible the Internet is to people with disabilities. What is the appropriate sample size? We should draw in order to start making our grand conclusions?

I went down Google/​Perplexity rabbit hole trying to figure out an appropriate answer. I am left with more questions than when I started, so I turned to the LW community.